p Step 1: Prepare your dentures by washing thoroughly with warm water. Be sure that your dentures are still wet before applying adhesive powder.br Step 2: To apply the Fixodent adhesive powder to your dentures, gently squeeze or tap the bottle. For best results, cover the entire surface of the part of the denture that touches the gum with a thin, even layer of powder. Shake off any excess powder.br Step 3: Press your dentures firmly into place and hold briefly.